Proton-pump inhibitors (PPIs) are a group of drugs whose main action is a pronounced and long-lasting reduction of gastric acid production. They are the most potent inhibitors of acid secretion available. The group followed and has largely superseded another group of pharmaceuticals with similar effects, but a different mode of action, called H2-receptor antagonists. These drugs are among the most widely sold drugs in the world, and are generally considered effective.
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American scientists conducted a study that showed that gastroesophageal reflux disease, one of the manifestations of which is heartburn, is associated with a high risk of developing cancer of the larynx and...