The hypodermis, also called the hypoderm, subcutaneous tissue, subcutis, or superficial fascia, is the lowermost layer of the integumentary system in vertebrates. Hypoderm and subcutaneous are from Greek and Latin words, respectively, for “beneath the skin. ” Types of cells that are found in the hypodermis are fibroblasts, adipose cells, and macrophages. It is derived from the mesoderm, but unlike the dermis, it is not derived from the dermatome region of the mesoderm.
